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Help! How Do I Get Rid Of House Mice On My Jacksonville, FL Property?

Dec 3, 2025


If you’ve spotted tiny droppings under the sink, heard scratching in the walls, or noticed a few mysterious chew marks on pantry items, there’s a good chance house mice are making themselves comfortable inside your Jacksonville home. These critters may look small and harmless, but they can create big problems, especially in Florida’s mild climate, where mice remain active year-round.

House mice thrive in Greater Jacksonville, from quiet suburban neighborhoods to dense urban areas, because our homes offer them everything they need: warmth, shelter, and abundant food sources. Whether you’re in a historic Riverside bungalow, a beachside home in Jax Beach, or a modern townhome near the urban core, understanding how to identify, prevent, and eliminate mice is essential for Northeast Florida homeowners.

What This Blog Covers

  • What house mice look like and why they’re so common in Jacksonville
  • The damage mice cause and the health risks they bring
  • Practical rodent prevention tips 
  • Why DIY mouse control often fails
  • When to call a pest control company and what to expect
up close image of a house mouse walking on a piece of wood

How to Identify House Mice

House mice are small, quick, and surprisingly good at staying out of sight. Here's how to know what you’re dealing with:

  • Size: 5 ½ to 7 inches long from nose to tail
  • Tail: Long, thin, and lightly furred
  • Features: Large ears, small black eyes, pointed nose, long whiskers
  • Color: Golden brown to dark gray fur with a lighter belly

One important detail many homeowners don’t realize: juvenile roof rats can look similar to mice, but control methods differ. If you're unsure, always err on the side of professional identification.

Why House Mice Are a Big Problem

You may only see one mouse, but a single mouse sighting often means many more are hiding nearby. Mice reproduce quickly, explore constantly, and can cause serious issues inside your home.

Damage Caused by House Mice

  • Chewing on electrical wires (risk of shorts or house fires)
  • Damaging plumbing by gnawing on pipes
  • Tearing insulation, cardboard, and soft materials for nesting
  • Creating holes in walls, trim, and flooring
  • Ruining personal items such as books, linens, and stored decorations

Health & Sanitation Risks

Mice contaminate far more than they consume. They can spread:

  • Hantavirus
  • Salmonellosis
  • Leptospirosis
  • Plague (transmitted via infected fleas, still found in the U.S.)
  • Ticks & fleas
  • Allergens from droppings, urine, and shed fur

Even if mice never make direct contact with you, their droppings, urine trails, and nesting materials can contaminate food storage areas, countertops, and HVAC systems.

Effective House Mouse Prevention for Jacksonville Homes

Jacksonville’s warm, humid climate enables mice to remain active throughout all four seasons, making prevention a continuous, rather than occasional, necessity.

Here are practical, realistic steps to reduce your risk:

Outdoor Prevention 

  • Keep grass trimmed and remove leaf piles or yard debris.
  • Store firewood at least 20 feet from the house and off the ground.
  • Fix water-damaged siding, fascia, or soffits (moisture attracts rodents).
  • Clean gutters and eliminate sources of standing water.
  • Keep trash in bins with tight-fitting lids.

Indoor Prevention

  • Store pantry food in airtight containers, as mice can chew through boxes and bags.
  • Don’t leave pet food out overnight.
  • Repair leaky pipes or damp areas that attract pests.
  • Limit clutter, especially in attics, closets, and garages.
  • Clean crumbs under appliances and inside cabinets.

Seal Entry Points

Mice can squeeze through openings the size of a dime. Seal or repair:

  • Gaps around utility lines and plumbing
  • Openings around vents or crawlspace access
  • Cracks in the foundation or siding
  • Gaps under doors or garage weatherstripping

Even with excellent prevention, mice in the Sunshine State are incredibly resourceful, which is why many homeowners still experience infestations despite doing everything “right.”

Why DIY Mouse Control Often Fails

Trying to eliminate mice on your own often leads to:

  • Traps catch only a small fraction of the population
  • Mice avoiding traps altogether
  • Odors from mice dying inside the walls
  • Continued issues even after “a few are gone.”

Without understanding rodent behavior, including travel routes, nesting habits, breeding cycles, and food patterns, it’s nearly impossible to remove all mice, not just a few.

Professional Mouse Control for Jacksonville, FL

The most effective way to get rid of mice is through professional rodent control. At Lindsey Pest Services, our licensed technicians use proven, science-backed strategies to eliminate existing infestations and prevent them from returning.

When you partner with Lindsey, you’ll receive:

  • A full inspection to locate nests, entry points, and activity zones
  • Customized trapping, exclusion, and sanitation recommendations
  • Peace of mind knowing your home is mouse-free

For homeowners seeking long-term protection from mice and other house-infesting pests, we highly recommend signing up for one of our comprehensive home pest control plans. 

Ready to stop the scratching, chewing, and late-night scurrying? Contact Lindsey Pest Services today to protect your property and reclaim your home from unwanted house mice.

FAQ: House Mice in Jacksonville, FL 

What are the first signs of mice in a home?
Common signs include droppings, scratching sounds, gnawed food packaging, musky odors, and small holes or shredded materials used for nesting.

How do mice get into homes in Northeast Florida?
Mice squeeze through gaps as small as a dime. Common entry points include gaps around utility lines, damaged siding, crawlspace vents, garage doors, and areas with water damage.

Do mice go away on their own?
No. Once mice establish access to food and nesting sites, they rarely leave without targeted removal. Because Jacksonville’s climate is mild, they remain active year-round and can quickly grow their population if left untreated.

This blog was originally published on October 15, 2021; it has been updated to include new information. 

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